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In addition, since iron is heterogeneously distributed across brain regions and cell types (Levi et al., 2024), potential off-target chelation could result in iron depletion in brain regions where iron supports physiological function and consequently affect neuronal and glial metabolism, neurotransmitter synthesis, or cell signaling
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FDA treats any injectable product as a drug
Characteristics of the included studies In total, 20 studies were selected after meeting the inclusion criteria, including ten animal studies and nine human studies
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