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IGF-1 LR3 1 is a modified version of human IGF-1, extended by 13 amino acids and featuring a substitution at arginine-3 to reduce binding to IGF-binding proteins (IGFBPs)

In addition, we observed that GHK treatment downregulated AQP4 expression and decreased injury of astrocytes, likely via the upregulation of miR-146a-3p

Nature 575 (7784), 693698

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Br J Nutr (2007) 98(Suppl 1):S1115.10.1017/s0007114507838049 51 WichmanJWintherKHBonnemaSJHegedusL