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Collectively, these OFF-to-ON switching strategies illustrate therapeutic approaches in which GSH acts as a biological trigger for selective activation of cytotoxic agents in the GSH-rich tumor microenvironment

A wide variation in centrifugation conditions has been reported, from 200 g for 20 min to 1500 g for 25 min

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Inhibition of NNMT: 1-MNA has been shown to inhibit the enzyme NNMT, which when present in high levels, is associated with various diseases