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One study found that targeting senescent p21 high cells in adipose tissue using a senolytic cocktail, dasatinib with quercetin, alleviated insulin resistance in obesity [37]
Xu Y, Shen J, Ran Z
Pigment Transfer in Skin Cells
This finding is particularly important given the obesity population's inherent cardiovascular risk
Originally developed as an anti obesity compound, it has become a widely used research tool for studying fat metabolism, lipolysis, and more recently cartilage repair, valued particularly for its ability to mimic the fatmetabolizing activity of growth hormone without the broader hormonal side effects that come with it
So I wanna, you know, repeat some labs and I wanna understand that if, if there's a very clear hypoglycemia, hyperglycemia, insulin resistance, certainly with a complaint of difficulty losing weight, even if they're not overweight, but they feel like they they are, or they're puffy or they feel like there's some, there's some quite classic things that I see that are really metabolic and, and rooted in Mast Cell Activation Syndrome
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