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10.1161/01.CIR.0000109496.82683.49 Circulation 165 ShimamuraM.SatoN.WaguriS.UchiyamaY.HayashiT.IidaH.et al (2006)

Some peptides have limited research in animals, such as rats, that indicates they could promote wound healing or reduce inflammation

BPC 157 expressing egr1 mRNA was observed after 15 min, followed by almost immediate expression of nab2 mRNA [100]

A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight (NCT04881760)

Thats led to interest in microdosing protocols, personalized/alternative dosing, and extended interval strategies to try to optimize benefits while reducing downsides