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In vitro and in vivo drug metabolism analysis of BPI-460372 - A covalent TEAD1/3/4 inhibitor

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These cells can arise from various sources, including the transdifferentiation of resident fibroblasts (fibroblast-to-myofibroblast transition, FMT), epithelial cells (epithelial-to-mesenchymal transition, EMT), or endothelial cells (endothelial-to-mesenchymal transition, EndMT) [86]

It is a chronic skin disease that affects millions of people worldwide

Treatments, alone or combined, returned total motility to control levels (Fig