Overall, the proteomic data indicated that semaglutide effectively mitigated hepatic lipid deposition and key pathways related to fatty acid/lipid protein signalling and fibroblast proliferation ( Figure S11 ), further supporting our histological and single-cell RNA sequencing findings
The inclusion of L-Carnitine, Methionine, Choline, and Inositol allows investigation of pathways associated with lipid transport, mitochondrial oxidation, and hepatic metabolic activity
the upstream mechanism is still being mapped
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One of the most influential factors is a person's biology, including age, sex, and body weight