Patients should not discontinue statins in favour of GLP-1 therapy for cholesterol management without explicit guidance from their healthcare provider, as this could compromise cardiovascular risk reduction
GLP-1 is a 30 amino acid peptide produced by the L cells, enteroendocrine cells of the distal ileum and colon, and GIP is a 4 amino acid peptide produced by the K cells of the duodenum and jejunum
Generally, you may be a good candidate for GLP-1 therapy if: You have a body mass index (BMI) that falls within a certain range, typically 27 or higher with a weight-related health condition, or 30 or higher without one
The NHS website (nhs.uk) provides patient-facing information on weight management services and referral pathways
Retatrutide is a next-generation triple agonist peptide targeting the GIP (glucose-dependent insulinotropic polypeptide) , GLP-1 (glucagon-like peptide-1) , and glucagon receptors
April 13, 2022