Immunity 56 , 307319.e308 (2023)
The substances affected include BPC-157, LL-37, DiHexa, DSIP, Epitalon, injectable GHK-Cu, KPV, PEG-MGF, Melanotan II, MOTs-C, Semax, and TB-500
Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times
427 In addition, the mRNA level of HO-1 in the tissues was increased, while the mRNA amount of FtMt was decreased
Hallmarks of brain aging: Adaptive and pathological modification by metabolic states
Together, they deliver both instant and long-term improvements