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In real terms, the average participant lost about 27.5 pounds from a trial-wide average starting weight of about 236 pounds

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Intriguingly however, very recent data on anti-CD20 B cell depleting agents might be showing some efficacy in progressive MS, although the effect of peripheral B cell depletion on PIRA cannot be interpreted as independent of its effect on silencing acute/adaptive inflammatory activity (Kappos et al., 2020)