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The right protocol depends on factors like your baseline metabolic health, body composition, and other therapies you might be using

This is why providers use a titration schedule, which is the process of gradually increasing your dose over several months

Amount of weight loss: Weight loss also varied a lot in the trial, so researchers compared the health effects in those with a little versus a lot of relative weight loss

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These symptoms may indicate nutrient deficiencies particularly iron, B12, or vitamin D that are common during calorie restriction and easily identified with bloodwork

Its baked into the very biology of how these systems interact