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In addition, intestines are richly innervated by afferent sensory nerves expressing TRPV1 channels, and their activation plays an important role in the gut function regulation (5860)

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As a vital body component, vitamin B12 plays a role in DNA synthesis, red blood cell production, and neurological function

It also interacts with afferent and efferent signals from the CNS, enabling integration of local and systemic functions

Traditional calorie restriction requires constant mental effort to resist food urges