The treatment ratio (2.38) is a strong effect size
Facial cream containing GHK-Cu and melatonin increased collagen in photoaged skin of 20 female volunteers, performing better than vitamin C and retinoic acid
While hydroquinone is considered the gold standard for lightening dark spots, its results are significantly enhanced when combined with other proven ingredients like tretinoin, which speeds up cell turnover, and a mild corticosteroid, which reduces inflammation and irritation
10.1002/glia.23306 [DOI] [PMC free article] [PubMed] [Google Scholar] Hasegawa-Ishii S., Takei S., Chiba Y., Furukawa A., Umegaki H., Iguchi A., et al
Discontinuation implications here prove more favorable - once acute issues like scarring, hyperpigmentation, or inflammatory damage resolve through GHK-Cu treatment, improvements typically persist because underlying pathology has been corrected rather than merely suppressed
Therefore, we conducted a subgroup analysis
