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Background An increasing trend of Parkinson's disease (PD), as the neurodegenerative illness, has been reported, and it is more prevalent in countries with high human development and sociodemographic indicators (1)

In addition, only administration of GLP-1RA resulted into lower nonfatal strokes (OR, 0.88[0.77-0.99]) than those receiving placebo

Gillingham M, Connor WE, Matern D, Rinaldo P, Burlingame T, Meeuws K, et al

ChungKFWenzelSEBrozekJLBushACastroMSterkPJet alInternational ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

The central mechanism rests on activation of MC4R neurons in the paraventricular nucleus projecting to the preoptic area and limbic structures involved in sexual motivation, triggering a pro-erectile response in men and pro-libido response in women

Zapletal E, Vasiljevic T, Busson P, Matijevic GT