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Dysregulated glutathione metabolism links to impaired insulin action in adipocytes

J., Li, E

Among the environmental pollutants, polybrominated diphenyl ethers (PBDEs) represent a widely used type of flame retardants in commercial products and a main source of environmental contaminants

Although previous MMA mouse models recapitulate human disease, a model of MMA that has prolonged adult survival with the replication of the metabolic and clinical phenotypes seen in severe patients has not been developed

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Post-mortem cortical tissue from people with ASDshows significantly reduced MET protein levels, accompanied by dysregulation of HGF-MET co-expression, suggesting disrupted signaling pathways (117)