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Hypertension, ischemic heart disease, patients with atherosclerosis and coronary artery disease, diabetes, chronic lung diseases, smoking and obesity are associated with low baseline GSH levels and reduced GSH/oxidized glutathione (GSSG) ratios (Khanfar and Al Qaroot, 2020

Fiber is also essential to help manage digestion and prevent constipation

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Less Common but Serious: Pancreatitis Gallbladder disease Kidney issues (especially with dehydration) Vision changes Mood changes or depression Seek prompt medical attention if these occur

Those who need visible results quickly to maintain motivation

A systematic review of randomized controlled trials