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PNAS Nexus 4 , pgaf042 (2025)

Due to the close connection between this pathogenesis, it must be considered that drug manipulation of one of the diseases can also affect the other components of this interaction

The net effect is therefore positive, regardless of which pathway dominates

A 110 kDa protein that contains an N-terminal RAS-associated domain, a coiled-coil domain, a pleckstrin homology (PH) domain and a proline-rich C-terminal domain with six FPPPP motifs that binds to profilin and Ena and VASP family proteins

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