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It describes estrogen as a regulator of glucose metabolism, thermogenesis, and fat distribution, and says its decline shifts fat storage toward the abdomen while reducing metabolic rate by 2 to 8% after menopause

The most common side effects are mild and usually temporary: nausea, a feeling of fullness, or some digestive changes, especially when first starting or increasing your dose

Understanding your personal response to semaglutide means recognizing that genetics, baseline metabolic markers, and gastrointestinal sensitivity all influence how quickly you may advance doses and when adjustments should pause

Role of gut microbiota-gut hormone Axis in the pathophysiology of functional gastrointestinal disorders