can you lose weight with b12 injections Shots and Loss—Separating Fact from Fiction B12 Shots for Weight Loss:

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A vitamin B12 shortage can cause a variety of health issues, ranging from exhaustion to permanent neurological abnormalities

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If vitamin B12 is ingested in its free (or nonprotein bound form), it will bind to a carrier protein known as R-binders or transcobalamin I that is secreted by both the salivary glands in the oropharynx and the gastric mucosal cells within the stomach.1,2,8 The free vitamin B12 ingested by mouth will remain in the bound form with an R-binder until it reaches the second segment of the duodenum in the small intestine

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The methylcobalamin does not influence this effect