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These pathways form a component of a broader signaling network associated with growth hormone control and cellular metabolism

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In addition to the different study populations and study design in these trials, one potential reason for this heterogeneity in cardiovascular benefit is the structural differences among the GLP-1RAs used in these trials

Funding Open access funding provided by Slovenian Research Agency grants # P30298 and by tertiary research project of University Medical Centre Ljubljana # 20200112

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Ipamorelin, acting as a selective ghrelin receptor agonist, complements this effect by promoting controlled GH release without significantly influencing appetite or cortisol levels