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Random effects models are preferable when significant heterogeneity is expected because they account for variable underlying effects in estimates of uncertainty, including both within-study and between-study variances [27]

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We have previously shown that this is based on the differences in structure of the SH domains of these two different receptor substrates (14)

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Exosomes derived from human adipose mesenchymal stem cells improve ovary function of premature ovarian insufficiency by targeting SMAD