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Collectively, evidence from in vitro and in vivo studies delineates a coherent pathway from initial cellular damage and thyroid dysfunction to the breakdown of immune tolerance

however, the efficacy or safety of most investigational and clinical drugs is not ideal

Journal of Medical and Veterinary Mycology, 29 (2), 6372

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While these studies remain early-stage, the consistent finding across trials has been the acceptable safety profile of MSC therapy in clinical research settings