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Volume depletion and hypotension can occur with SGLT2 inhibitors due to osmotic diuresis, particularly in elderly patients, those taking diuretics, or individuals with impaired renal function

There appears to be some basis for this use with some caveats

Key points for pharmacies: Be cautious with marketing: Avoid calling compounded semaglutide safe and effective or comparing it directly to FDA-approved products

Orlistat should be completely removed from your body within 3 to 5 days