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This skin darkening is generally reversible with the help of B12 shots

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However, since peripheral 5HT may be more hormonal than neuronal, the precise mechanism (or consequences) of decreased 5HT in cardiac tissue remains to be determined

Coles, L.D., et al., Repeated-Dose Oral N-Acetylcysteine in Parkinsons Disease: Pharmacokinetics and Effect on Brain Glutathione and Oxidative Stress

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