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A narrative review published in Cureus searched PubMed, Embase, and Scopus through August 2025, examining the intersection of GLP-1 therapy and autoimmune thyroid disease

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Protein-binding As mentioned before, the GM metabolites, p-Cresol and indoxyl sulfate exhibit high protein binding capacity, are excreted by kidneys via tubular secretion, and accumulate with failing kidneys [79]

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