Acting on two complementary points of the same axis, the two compounds are studied together for a larger, cleaner GH pulse than either produces alone with Ipamorelin chosen specifically because it raises GH with minimal spillover onto cortisol (the stress hormone) or prolactin
It also exhibits immunomodulatory effects, stimulating the recruitment of immune cells and promoting the clearance of pathogens through phagocytosis (Scott et al., 2002)
Recognizing non-response allows pivoting to alternative approaches rather than continuing ineffective treatment
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