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Side effects and tolerability Common side effects for both include nausea, early satiety, gastrointestinal upset, and potential gallbladder issues

Patients with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, pancreatitis, or other relevant conditions should discuss those histories thoroughly with a Novi provider or another qualified healthcare professional before beginning treatment

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PMID 7598783.

It says this may alter an individual's stress response over time, which is part of its argument that stress management has to be personalized rather than generic