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Oral route data in rodents shows genuine GI-local effects, but systemic bioavailability from capsules is unquantified in humans, meaning dose-response claims for joints and tendons rely on injection-route animal studies

Nat Neurosci 9:119126 Shashidharan P, Huntley GW, Murray JM, Buku A, Moran T, Walsh MJ, Morrison JH, Plaitakis A (1997) Immunohistochemical localization of the neuron-specific glutamate transporter EAAC1 (EAAT3) in rat brain and spinal cord revealed by a novel monoclonal antibody

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Gentle exfoliation helps to remove dead skin cells that can dull your complexion, allowing fresh, radiant skin to emerge

Oncotarget 7, 1768117698

Because of these distinctions, oral NAD+ and oral glutathione can qualify as dietary supplements