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IL-10, an anti-inflammatory cytokine largely described to promote resolution of inflammation and prevent tissue damage (18), was shown to prevent such endothelial cell apoptosis (17), to preserve the expression of endothelial junction proteins, namely occludin and claudin 5 (16), and to maintain proper vascular permeability during inflammation (15)

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Decreased expression of adhesion molecules, such as endothelial-leucocyte adhesion molecule-1 (E-selectin), intercellular adhesion molecule-1 and vascular cell adhesion molecule-1, has been observed in human aortic endothelial cells cultured with ergothioneine (90)

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By age 60, that number drops to approximately 80 nanograms per milliliter

Clinical Studies and Research on Glutathione for Fatty Liver Disease Numerous clinical studies have explored the efficacy of glutathione supplementation in treating fatty liver disease