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[DOI] [PubMed] [Google Scholar] 50.Sikiric P., Seiwerth S., Rucman R., Turkovic B., Rokotov D.S., Brcic L., Sever M., Klicek R., Radic B., Drmic D., et al

In addition, degradation of membrane proteins residing on the limiting membrane of MVBs, such as VSRs, generally requires their sorting into intraluminal vesicles (ILVs) through ESCRT-dependent mechanisms 52

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This study illustrates the importance of inhibiting the glutathione metabolic pathway regulated by Nrf2 for tumor therapy, and at the same time provides a new idea for the treatment of malignant tumors with IDH1 mutations