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The closest safety dataset is the Increlex (mecasermin) clinical program , which followed 71 pediatric patients with severe primary IGFD on twice-daily SubQ rhIGF-1 for a mean of 3.9 years (some patients up to 11.5 years)

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Symptoms that may indicate Candida overgrowth include: Gas, bloating, or irregular digestion Sugar cravings Brain fog or fatigue Skin rashes or recurring flares A history of frequent antibiotic or steroid use Its also worth noting that skin and gut fungal overgrowths can exist together, compounding the problem

Adlakha-Hutcheon G, et al