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A minimal loss of lean mass is ideal, especially muscle tissue, as this helps to prevent frailty and is metabolically active

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This approach typically utilizes the threshold defined by the Medicines and Healthcare Products Regulatory Agency (MHRA) composite standard for signal identification

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ASL also contains cytokines, antimicrobial peptides, antiviral interferons, leukocytes, and several types of antioxidants [10, 11]