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One patient (Patient 2) cleared methotrexate to 0.77 mol/L after glucarpidase administration (Table 2)

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In mammals, sulforaphane can similarly upregulate stress-induced signaling pathways, including the Nuclear Factor Erythroid 2-related Factor 2 (NRF2) transcriptional pathway, which is conserved across mammalian species, but absent from plants (Gacesa et al., 2016

Autophagy regulates TGF- expression and suppresses kidney fibrosis induced by unilateral ureteral obstruction