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Incidence of brain metastases following trimodality therapy (TMT) in patients with esophageal and gastroesophageal (E-EGCJ) cancer

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This timeline reflects the biology of connective tissue healing: the critical proliferative and remodeling phases of tendon and ligament repair typically span four to eight weeks, and supporting angiogenesis and fibroblast migration during that window addresses the mechanistic bottlenecks in healing