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Tesamorelin: FDA-approved as Egrifta and Egrifta WR, but only for visceral fat reduction in HIV-associated lipodystrophy

Here's the nuance, though

Mechanistically, in a TEAD-dependent manner, YAP/TAZ induces the expression of SLC7A11, a key transporter maintaining intracellular glutathione homeostasis

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This process is associated with morphological alterations typical for apoptosis, like cell shrinkage, membrane blebbing, and phosphatidylserine (PS) translocation to the outer leaflet of the cell membrane phospholipid bilayer [22, 23]

Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW