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S1PR2, located both in the liver and in the brain, activates the ERK and AKT pathways that regulate cell survival, inflammation, and stress response in the CNS

British Journal of Pharmacology / NIHMS PMC (2008) 6

J., Chung, J

[2] Reduces Inflammation: Oxidative stress triggers inflammation

141 GST inhibitors and their therapeutic implications GST inhibitors are compounds designed to impede the activity of GSTs, with significant therapeutic implications across various medical conditions

As dopamine has substantial impacts on cytokine production, migration, and other immune functions, exposure to elevated dopamine is likely to dysregulate these functions