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Hippocampal neurons transfected with mRFP-p-actin were treated with 10 ' 2 M dihexa or 10 "12 M Nle'-Ang IV for 5 days or 30 minutes in culture prior to fixation on day in vitro 12 (DIV12)

The broad pattern for acute injuries and post-surgical contexts in the data sits between four and eight weeks

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How IGF-1 LR3 Works Reduced IGFBP binding The N-terminal extension and R3 substitution disrupt binding to IGF-binding proteins, keeping LR3 free in plasma rather than sequestered

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