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Taken together, these results suggest that the contribution of TMAO to CHD may be substantially influenced by diet, renal function, medication exposure, and population characteristics, underscoring the importance of considering these confounders when interpreting TMAOcardiovascular associations

[6] Caution is also needed when using them with alpha-blockers and in patients with recent stroke or myocardial infarction

During August 2021-August 2023, approximately 2 in 5 adults were living with obesity in the United States [2]

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As initial appetite suppression fades, portion sizes may unconsciously increase, or food choices may drift from the structured eating patterns that supported early weight loss

its a fundamental change in how chronic conditions can be managed, with oral therapies set to expand access, simplify administration, and enhance adherence