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Constipation can happen during GLP-1 therapy because appetite, fluid intake, fiber intake, movement, and digestion may all change

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doi:10.1016/j.ajo.2025.02.025 34

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doi: 10.1056/NEJMoa1901118 55 RosenstockJAllisonDBirkenfeldALBlicherTMDeenadayalanSJacobsenJBet al

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The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects

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This side effect helped the drug soar in popularity, even though Ozempic hasnt been approved by the FDA for weight loss

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They appear most strongly during the first 1-2 weeks after each dose increase, then gradually subside as your body adapts to the new level of receptor activation

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