Constipation can happen during GLP-1 therapy because appetite, fluid intake, fiber intake, movement, and digestion may all change
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doi: 10.1056/NEJMoa1901118 55 RosenstockJAllisonDBirkenfeldALBlicherTMDeenadayalanSJacobsenJBet al
The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects
This side effect helped the drug soar in popularity, even though Ozempic hasnt been approved by the FDA for weight loss
They appear most strongly during the first 1-2 weeks after each dose increase, then gradually subside as your body adapts to the new level of receptor activation