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Indeed, the basal oxygen consumption rate (OCR) of Gclc -deficient FoB measured by extracellular flux analysis was slightly reduced compared to Gclc fl/fl FoB (Fig

However, intranasal administration is also considered an efficient route for systemic effects due to the dense vasculature of the nasal mucosa

Disclosure The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

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The majority of patients will notice a great deal of relief within 15 minutes after the injection

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