Hydroxocobalamin bonds to the body's transport molecules and circulates much longer in the blood than all other forms of vitamin B12, ensuring a long-lasting and balanced vitamin B12 supply
High B12 blood serum levels can often mean: The body is having trouble converting, transporting and absorbing vitamin B12 into the cells where it's needed for intracellular and downstream processes The vitamin B12 in your serum is inactive and not able to be utilized You could also have contributing deficiencies in iodine, selenium, molybdenum, and/or B21 And it can also mean that youre getting a form of B12 in your diet (or vitamins) that is not converting well in your body for absorption (likely cyanocobalamin) Ironically, this is called a paradoxical B12 deficiency
You may also come across adenosylcobalamin and hydroxocobalamin in supplements
This makes methylcobalamin injections a more direct and potent option for replenishing B12 stores
NNMT is a cytosolic S-adenosyl-L-methionine-dependent methyltransferase that converts nicotinamide to 1-methylnicotinamide, spending SAM and diverting nicotinamide away from the NAD+ salvage pathway
Note: All dosing should follow the prescribers orders