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In humans, the HTMLA activity is partially compensated by serine hydroxymethyl transferase (SHMT) 1 and 2, while in mice, threonine aldolase (Tha1) is the primary source of HTMLA activity, but this gene is absent in humans [159].The liver and kidney are considered the primary organs involved in carnitine synthesis because of their considerable BBD activity

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The method is generally employed to estimate the sample concentration of GSH plus GSSG, i.e., total GSH (tGSH), while addition of a SH masking agent to the sample allows for accurate and precise estimation of GSSG even at the very low levels

Takahira, Y