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The NRF2 activator, dimethyl fumarate, is clinically used to treat moderate to severe psoriasis [40], and various derivatives of it hold potential for treating psoriasis [41]

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Efficacy and safety of co-administered once-weekly Cagrilintide 2.4 mg with once-weekly semaglutide 2.4 mg in type 2 diabetes: a multicentre, randomised, double-blind, active-controlled, phase 2 trial