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everolimus XL309XL309 / USP1 / USP1 inhibitor / OncologyMultiple solid tumorsPhase 1XL309 or XL309 + olaparib XB010XB010 / 5T4 / Next-generation 5T4-MMAE ADC / OncologyMultiple solid tumorsPhase 1XB010 or XB010 + pembrolizumab XB628XB628 / PD-L1 + NKG2A / Bispecific antibody / OncologyMultiple solid tumorsPhase 1Ongoing clinical study XB371XB371 / Tissue factor / Next-generation TF-TOPOi ADC / OncologyMultiple solid tumorsPhase 1Ongoing clinical study ADU-1805ADU-1805 / SIRP / SIRP-targeting mAb / OncologyMultiple solid tumorsPhase 1ADU-1805 or ADU-1805 + pembrolizumab XB773XB773 / DLL3 / DLL3-TOPOi ADC / OncologyNot disclosedDiscovery/PreclinicalDiscovery/Preclinical SSTR2 AgonistSomatostatin receptor subtype 2 / SSTR2 agonist program development candidate / OncologyNot disclosedDiscovery/PreclinicalDiscovery/Preclinical 8assets TebentafuspKIMMTRAK / gp100 (HLA-A*02) / ImmTAC (TCR bispecific) / Oncologymetastatic uveal melanomaApprovedmarketedUSEUadjuvant uveal melanomaPhase 3ongoing 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Genetic DiseasesCystic FibrosisPhase 2aActive SION-451SION-451 / NBD1 (Nucleotide Binding Domain 1 of CFTR) / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 1Active SION-638SION-638 / NBD1 (Nucleotide Binding Domain 1 of CFTR) / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 1Active SION-109SION-109 / ICL4 (Intracellular Loop 4 of CFTR) / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 1Active GalicaftorABBV-2222 / TMD1-directed CFTR corrector / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 2Active NavocaftorABBV-3067 / CFTR potentiator / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 2Active ABBV-2851ABBV-2851 / TMD1-directed CFTR corrector / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPhase 1Active SION-676SION-676 / TMD1-directed CFTR corrector / Small Molecule / Respiratory / Genetic DiseasesCystic FibrosisPreclinicalActive 8assets SRP-1001SRP-1001 / FSHD1 / siRNA / NeuromuscularFacioscapulohumeral muscular dystrophy, Type 1 (FSHD1) SRP-1003SRP-1003 / DM1 / siRNA / NeuromuscularMyotonic dystrophy, Type 1 (DM1) SRP-1002SRP-1002 / siRNA / PulmonaryIdiopathic pulmonary fibrosis (IPF) SRP-1004SRP-1004 / siRNA / NeurologySpinocerebellar ataxia type 2 (SCA2) SRP-1005SRP-1005 / siRNA / NeurologyHuntington's disease (HD) SRP-1007SRP-1007 / siRNA / NeurologySpinocerebellar ataxia type 1 (SCA1) SRP-1006SRP-1006 / siRNA / NeurologySpinocerebellar ataxia type 3 (SCA3) bidridistrogene xeboparvovecSRP-9003 / LGMD2E/R4 -sarcoglycan / Gene Therapy / NeuromuscularLimb-girdle Muscular Dystrophy 8assets 8assets ZanidatamabZW25 / Ziihera / HER2 / Bispecific Antibody / OncologyBiliary Tract Cancer (BTC)ApprovedActiveUSEuropeGastroesophageal Adenocarcinoma (GEA)Phase 3ActiveGlobalBreast Cancer (Neoadjuvant and Adjuvant)Phase 2ActiveGlobal ZW191ZW191 / FR / Antibody-Drug Conjugate (ADC) / OncologyAdvanced Solid Tumors (Ovarian/Gynecological and Lung/Thoracic)Phase 1ActiveGlobal ZW251ZW251 / GPC3 / Antibody-Drug Conjugate (ADC) / OncologyHepatocellular Carcinoma (HCC) / Solid TumorsPhase 1ActiveGlobal ZW220ZW220 / NaPi2b / Antibody-Drug Conjugate (ADC) / OncologyGynecological and Thoracic CancersPreclinicalActiveGlobal ZW209ZW209 / DLL3 x CD3 x CD28 / Trispecific T-Cell Engager / OncologyThoracic CancersPreclinicalActiveGlobal ZW1528ZW1528 / IL-4R x IL-33 / Bispecific Antibody / Autoimmune / Inflammatory DiseasesRespiratory InflammationPreclinicalActiveGlobal PasritamigJNJ-78278343 / CD3 / Prostate Target / Bispecific Antibody / OncologySolid TumorsClinicalActiveGlobal DS-2243DS-2243 / T-Cell Engager / Bispecific T-Cell Engager / OncologyAdvanced Solid TumorsPhase 1ActiveGlobal 7assets OlverembatinibHQP1351 / BCR-ABL / small molecule TKI / OncologyCML-CP/AP with T315I