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170 WuJ.RenW.LiL.LuoM.XuK.ShenJ.et al (2018)

Iron deficiency anemia (IDA) may be the only symptom in about 40% of newly diagnosed celiac patients

found increased lipid peroxidation and increased acyl-CoA synthetase long-chain family member 4 (a pro-ferroptosis enzyme) in the renal tubules of lupus nephritis patients and mice

Although direct CNS administration of leptin or MC4R agonists may not be feasible for clinical studies or therapy for MI in humans, new MC4R agonists, such as setmelanotide, cross the blood brain barrier and can be administered peripherally and are already approved by the FDA to treat rare forms of genetic obesity

The adverse effect of elevated blood sugar on the glycocalyx is a primary reason why diabetes dramatically increases the risk of heart disease

Improved Cognitive Function : Supports mental clarity, focus, and mood stability