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More recently, however, an animal study based on a tandem stenosis mouse model showed the ability of SGLT2is to stabilize atherosclerotic plaques, with increased fibrosis, augmented collagen accumulation, and significant upregulation of the expression of vasculoprotective NADPH oxidase 4 [18]

Mortality and survival: comparison of eunuchs with intact men and women in a mentally retarded population

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Whether it is TIDM or TIIDM, if patients do not treat their hyperglycemia through appropriate medical interventions, they may face a series of severe consequences like blindness, kidney failure, or amputation

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Stratification by cumulative dosage showed that higher cumulative dosage was associated with decreased rates of relapse