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That was one of the reasons for the many years it took to get anywhere with this

Therefore, we align your plan with realistic expectations

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Although side effects seem to be in line with other weight loss drugs, long-term safety and real-world data will take time to build

In DKD, ERS is primarily triggered by hyperglycemia, proteinuria, and the presence of AGEs and free fatty acids ( A recent study has revealed that ERS can increase the levels of unsaturated triacylglycerol precursors and reduce lipid droplet formation, leading to tubular injury and fibrosis in renal proximal tubular cell lines and STZ-induced diabetic mouse kidneys (83)