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[210] The timing of administration plays a crucial role in optimizing therapeutic benefits while minimizing next-day sedation

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Upon FCCP treatment, the ETC activity rate increases in the attempt to restore the proton gradient and re-couple it to OXPHOS

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Also, as mentioned above, the adenosylcobalamin cofactor catalyzes a number of bioprocesses [18, 29,30,31], with 12 bioprocesses identified to date [4, 32,33,34,35,36,37]