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In breast cancer cells, AGR2 expression decreases the degradation of HIF-1 and increases MDR1 transcription, thus decreasing epirubicin uptake and promoting doxorubicin ( DOX ) resistance in breast cancer cells 42

Of note, blood NAD metabolites were changed in all studied diseases, except for prostate cancer, while glutathione metabolites demonstrated alteration only in cancers (Fig

Symptoms include sudden shortness of breath, persistent coughing, chest pain, rapid heartbeat, confusion, and a feeling of impending doom

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Boeckx, R.L