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In M mice, MGF was expressed using the HD locus promoter which was modified to include lac operators and in R mice, the human -actin promoter was used to drive the Lac-I gene expression

[DOI] [PMC free article] [PubMed] [Google Scholar] 278.Ayi K, Lu Z, Serghides L, Ho JM, Finney C, Wang JCY, et al

Nakanishi, and O

(Peptide Sciences) While senescence is protective in acute contexts (e.g., preventing malignant transformation, wound repair), the accumulation of senescent cells over time is detrimental: They occupy tissue space and resources, impairing progenitor cell function

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Dilution itself doesn't degrade the peptide